Immunohistochemistry theses build on the archive of paraffin blocks every histopathology department holds, which is why retrospective designs dominate this area. The sample titles relate ER, PR, HER2, HER2-low status, androgen receptor and Ki-67 to grade and subtype in breast carcinoma, and use p16 in cervical neoplasia, mismatch repair proteins in colorectal cancer, PD-L1 in oral cancer and marker panels for lymphoma.
The real constraint is antibody cost and supply. Confirm which markers the department already runs, and whether extra antibodies can be funded, before choosing a topic. Block quality matters, since poor fixation produces false negatives. Retrospective use of archived tissue still needs ethics approval, and clinical details such as stage or follow-up should be retrievable from records.
1Immunohistochemistry & Molecular Pathology: catalogue at a glance
Our catalogue (shared with medicalthesistopic.in) has 80 MD Pathology titles in Immunohistochemistry & Molecular Pathology. Study designs used most often in this area:
| Study design | Titles |
|---|---|
| Retrospective record-based study | 59 |
| Analytical cross-sectional study | 13 |
| Prospective analytical study | 4 |
| Prospective observational study | 2 |
| Community-based cross-sectional study | 1 |
| Hospital-based cross-sectional study | 1 |
This page is part of MD Pathology thesis topics.
233 Immunohistochemistry & Molecular Pathology thesis titles
Free to read, newest first. Each has two optional paid add-ons on medicalthesistopic.in: objectives (₹50) and a full plan / synopsis (₹500) for that exact title, paid separately there.
- 001
ERG immunohistochemistry in prostatic adenocarcinoma and its association with ISUP grade group and serum PSA
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 002
CD117 and DOG1 immunohistochemical expression in gastrointestinal stromal tumours and association with risk category
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 003
ALK D5F3 immunohistochemistry in lung adenocarcinoma and its concordance with fluorescence in situ hybridisation
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 004
EGFR mutation testing by real-time PCR in non-small cell lung carcinoma biopsies and its association with histological subtype and smoking
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 005
Ki-67 index versus mitotic count for grading gastroenteropancreatic neuroendocrine tumours: a concordance study
Immunohistochemistry & Molecular PathologyRetrospective record-based studyComparative Study - 006
HER2 immunohistochemical expression in urothelial carcinoma and its association with grade and muscle invasion
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 007
MYC and BCL2 dual expression in diffuse large B-cell lymphoma and its association with clinical stage and International Prognostic Index
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 008
WT1, PAX8 and p53 immunoprofile in high-grade serous carcinoma versus other ovarian epithelial tumours
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 009
STAT6 immunohistochemistry in the diagnosis of solitary fibrous tumour and its distinction from histological mimics
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 010
PD-L1 combined positive score in squamous cell carcinoma of the cervix and its association with FIGO stage
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 011
INSM1 versus synaptophysin and chromogranin immunohistochemistry in the diagnosis of neuroendocrine neoplasms
Immunohistochemistry & Molecular PathologyRetrospective record-based studyComparative Study - 012
HER2 immunohistochemistry in gastric and gastro-oesophageal junction adenocarcinoma and its association with Lauren histological type
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 013
p53 immunohistochemistry patterns in endometrial carcinoma as a surrogate for molecular classification and their association with histological type
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 014
PRAME and SOX10 immunohistochemistry in distinguishing cutaneous melanoma from benign melanocytic naevi
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 015
IDH1 R132H and ATRX immunohistochemistry in diffuse gliomas and integration with histological diagnosis
Immunohistochemistry & Molecular PathologyRetrospective record-based studyClinical Spectrum / Profile - 016
Estrogen and progesterone receptor expression in endometrial carcinoma and its association with histological grade
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 017
Calretinin immunohistochemistry in the diagnosis of Hirschsprung disease on rectal biopsies
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 018
Immunohistochemistry on cell blocks of serous effusions in distinguishing reactive mesothelial cells from metastatic carcinoma
Immunohistochemistry & Molecular PathologyProspective analytical studyDiagnostic Accuracy - 019
Immunohistochemical expression of p53 and Ki-67 in urothelial carcinoma and its association with grade and stage
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 020
CK7 and CK20 immunoprofile in carcinomas of unknown primary and its utility in predicting site of origin
Immunohistochemistry & Molecular PathologyRetrospective record-based studyDiagnostic Accuracy - 021
Immunohistochemical expression of BCL-2 and CD10 in diffuse large B-cell lymphoma and cell-of-origin classification by the Hans algorithm
Immunohistochemistry & Molecular PathologyRetrospective record-based studyClinical Spectrum / Profile - 022
PD-L1 expression in oral squamous cell carcinoma and its association with tumour stage and nodal status
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 023
Mismatch repair protein expression by immunohistochemistry in colorectal carcinoma and its clinicopathological correlates
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 024
p16 immunohistochemistry in cervical intraepithelial neoplasia and its role in grading cervical lesions
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyDiagnostic Accuracy - 025
Ki-67 proliferation index in meningiomas and its correlation with WHO grade
Immunohistochemistry & Molecular PathologyRetrospective record-based studyAssociation / Correlation - 026
TRPS1 immunohistochemistry in breast carcinoma and its comparison with GATA3 as a breast lineage marker
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyComparative Study - 027
Androgen receptor expression in triple-negative breast carcinoma and its association with tumour grade and Ki-67
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 028
Expression of HER2 in breast carcinoma with emphasis on HER2-low status and its association with clinicopathological factors
Immunohistochemistry & Molecular PathologyAnalytical cross-sectional studyAssociation / Correlation - 029
Role of immunohistochemistry panel in subtyping of lymphoma in lymph node biopsies
Immunohistochemistry & Molecular PathologyHospital-based cross-sectional studyAssociation / Correlation - 030
Correlation of Ki-67 index with molecular subtype in invasive breast carcinoma
Immunohistochemistry & Molecular PathologyProspective analytical studyOutcome / Prognostic - 031
Association of ER, PR and HER2 status with histological grade and lymph node status in invasive breast carcinoma
Immunohistochemistry & Molecular PathologyCommunity-based cross-sectional studyCommunity / KAP - 032
Expression of Ki-67 in thyroid neoplasms and its correlation with histopathological type
Immunohistochemistry & Molecular PathologyProspective observational studyClinical Spectrum / Profile - 033
Pattern of cervical precancerous lesions on cervical biopsy with p16 immunohistochemistry
Immunohistochemistry & Molecular PathologyProspective observational studyClinical Spectrum / Profile
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4Tips for a Immunohistochemistry & Molecular Pathology thesis
- Score hormone receptors with the Allred score or H-score and HER2 with ASCO/CAP guideline criteria, and state which version you followed in the methods.
- Run positive and negative controls with every batch, and have a second pathologist score a subset blinded to clinical data to show inter-observer agreement.
- Count Ki-67 in hotspots or across the whole section by a fixed, stated method, since different counting approaches give results that cannot be compared.
Other MD Pathology subject areas: Cytopathology · Haematology · Surgical Pathology & Histopathology · Clinical Pathology · Laboratory Quality Management
Before you finalise a title, read how to choose a thesis topic and how to write aims and objectives.
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❓ Frequently Asked Questions
Quick answers to common questions on this topic
It currently has 80 MD Pathology titles in Immunohistochemistry & Molecular Pathology; this page lists 33 of them. The most common designs are retrospective record-based study, analytical cross-sectional study.
Yes. Under each title there are buttons for objectives (₹50) and a full plan or synopsis (₹500). They open the title on medicalthesistopic.in, where you pay separately and get the draft on screen to edit with your guide.
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