Depression and bipolar disorder are the core of most psychiatry outpatient and inpatient services, so the challenge here is choosing a sharp question rather than finding patients. The sample titles compare lithium with valproate in mania, test behavioural activation alongside medication, follow antidepressant response, and look at sleep, metabolic syndrome, white matter changes and caregiver burden.
Treatment studies need weeks of follow-up and consistent rating by one assessor, and randomised designs require ethics approval and trial registration. Bipolar work should define mood state at assessment, since euthymic, manic and depressed patients differ sharply. Suicide risk must be screened and acted upon, with a clear referral pathway written into the protocol.
1Mood Disorders: catalogue at a glance
Our catalogue (shared with medicalthesistopic.in) has 50 MD Psychiatry titles in Mood Disorders. Study designs used most often in this area:
| Study design | Titles |
|---|---|
| Hospital-based cross-sectional study | 21 |
| Prospective observational study | 6 |
| Prospective analytical study | 5 |
| Retrospective record-based study | 5 |
| Analytical cross-sectional study | 4 |
| Prospective comparative study | 4 |
This page is part of MD Psychiatry thesis topics.
239 Mood Disorders thesis titles
Free to read, newest first. Each has two optional paid add-ons on medicalthesistopic.in: objectives (₹50) and a full plan / synopsis (₹500) for that exact title, paid separately there.
- 001
Aripiprazole augmentation versus switching to another antidepressant in major depressive disorder not responding to an adequate SSRI trial
Mood DisordersProspective comparative studyComparative / Interventional - 002
Functional impairment on the Functioning Assessment Short Test and its clinical correlates in euthymic patients with bipolar disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 003
Prevalence and clinical correlates of the DSM-5 mixed features specifier in patients presenting with a major depressive episode
Mood DisordersHospital-based cross-sectional studyClinical Spectrum / Profile - 004
Early improvement at two weeks as a predictor of response and remission at eight weeks of SSRI treatment in major depressive disorder
Mood DisordersProspective observational studyOutcome / Prognostic - 005
Clinical correlates of rapid cycling in bipolar disorder and its association with antidepressant exposure
Mood DisordersHospital-based cross-sectional studyClinical Spectrum / Profile - 006
C-reactive protein and neutrophil-to-lymphocyte ratio in acute mania compared with euthymic bipolar disorder
Mood DisordersAnalytical cross-sectional studyAssociation / Correlation - 007
Escitalopram versus sertraline in first-episode major depressive disorder: response and remission at eight weeks
Mood DisordersProspective comparative studyComparative / Interventional - 008
Residual symptoms and their association with functional outcome in remitted major depressive disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 009
Hypomania Checklist-32 for detecting bipolarity among patients presenting with a major depressive episode
Mood DisordersHospital-based cross-sectional studyDiagnostic / Tool Evaluation - 010
Serum vitamin D levels in major depressive disorder and their correlation with symptom severity
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 011
Comorbid anxiety disorders in bipolar disorder and their association with psychosocial functioning
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 012
Clinical predictors of response to lithium prophylaxis over one year in bipolar I disorder
Mood DisordersProspective observational studyOutcome / Prognostic - 013
Serum homocysteine in major depressive disorder and its correlation with symptom severity
Mood DisordersAnalytical cross-sectional studyAssociation / Correlation - 014
Internalised stigma and its association with treatment adherence in bipolar disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 015
Renal and thyroid function in patients on long-term lithium therapy in relation to serum lithium levels
Mood DisordersRetrospective record-based studyClinical Spectrum / Profile - 016
Sleep quality and circadian preference in patients with recurrent depressive disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 017
Relapse rate and its predictors in bipolar disorder over one year of follow-up
Mood DisordersProspective observational studyOutcome / Prognostic - 018
Diagnostic accuracy of the Hindi PHQ-9 against clinical interview for depression in medical outpatients
Mood DisordersHospital-based cross-sectional studyDiagnostic / Tool Evaluation - 019
Childhood adversity and temperament as predictors of illness severity in major depressive disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 020
Thyroid function abnormalities in first-episode major depressive disorder
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 021
Clinical correlates of treatment-resistant depression and response to augmentation strategies
Mood DisordersProspective observational studyOutcome / Prognostic - 022
Cognitive deficits in euthymic patients with bipolar I disorder compared with healthy controls
Mood DisordersAnalytical cross-sectional studyAssociation / Correlation - 023
Prevalence of metabolic syndrome in patients with bipolar disorder on maintenance mood stabilisers
Mood DisordersHospital-based cross-sectional studyClinical Spectrum / Profile - 024
Serum brain-derived neurotrophic factor in drug-naive major depressive disorder and its change after eight weeks of escitalopram
Mood DisordersProspective analytical studyAssociation / Correlation - 025
Usefulness of the Mood Disorder Questionnaire in detecting bipolar disorder among patients presenting with depression
Mood DisordersProspective analytical studyDiagnostic / Tool Evaluation - 026
Predictive value of social support score for caregiver burden in depression at a tertiary care hospital
Mood DisordersHospital-based cross-sectional studyAssociation / Correlation - 027
Prevalence of thyroid dysfunction in patients with major depressive disorder
Mood DisordersRetrospective record-based studyClinical Spectrum / Profile - 028
Determinants of severity in patients admitted with bipolar disorder at a tertiary care hospital
Mood DisordersRetrospective record-based studyOutcome / Prognostic - 029
Comparative efficacy of lithium versus sodium valproate in acute mania assessed by the Young Mania Rating Scale
Mood DisordersProspective interventional studyComparative / Interventional - 030
Clinical profile and predictors of severity in patients with depression at a tertiary care hospital
Mood DisordersHospital-based cross-sectional studyOutcome / Prognostic - 031
Effectiveness of family psychoeducation on caregiver burden among caregivers of patients with bipolar disorder
Mood DisordersProspective interventional studyComparative / Interventional - 032
Clinical significance of sleep quality in predicting functional impairment among patients with depression at a tertiary care hospital
Mood DisordersProspective analytical studyAssociation / Correlation - 033
Sleep quality in euthymic patients with bipolar disorder and its association with risk of relapse
Mood DisordersRetrospective record-based studyAssociation / Correlation - 034
Effectiveness of brief behavioural activation added to pharmacotherapy versus pharmacotherapy alone in major depressive disorder
Mood DisordersQuasi-experimental studyComparative / Interventional - 035
Prevalence of metabolic syndrome in patients with bipolar disorder on mood stabilisers and its impact on quality of life
Mood DisordersProspective observational studyClinical Spectrum / Profile - 036
Burden and coping strategies among caregivers of patients with bipolar disorder
Mood DisordersProspective analytical studyClinical Spectrum / Profile - 037
Prevalence of depression and its association with academic stress among undergraduate medical students
Mood DisordersHospital-based cross-sectional studyClinical Spectrum / Profile - 038
Prescription pattern of antidepressants and treatment response at 12 weeks in patients with major depressive disorder
Mood DisordersProspective analytical studyClinical Spectrum / Profile - 039
MRI white matter hyperintensities in patients with bipolar disorder and their correlation with cognitive functioning
Mood DisordersHospital-based cross-sectional studyClinical Spectrum / Profile
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4Tips for a Mood Disorders thesis
- Rate severity with HAM-D or MADRS for depression and the Young Mania Rating Scale for mania, and define response and remission thresholds before recruiting.
- Confirm euthymia in bipolar studies with low scores on both mania and depression scales at assessment, and record the mood stabiliser and its serum level.
- For metabolic syndrome, use a named definition such as NCEP ATP III with fasting samples, and record antipsychotic co-prescription as a confounder.
Other MD Psychiatry subject areas: Substance Use Disorders · Psychotic Disorders · Consultation-Liaison Psychiatry
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❓ Frequently Asked Questions
Quick answers to common questions on this topic
It currently has 50 MD Psychiatry titles in Mood Disorders; this page lists 39 of them. The most common designs are hospital-based cross-sectional study, prospective observational study.
Yes. Under each title there are buttons for objectives (₹50) and a full plan or synopsis (₹500). They open the title on medicalthesistopic.in, where you pay separately and get the draft on screen to edit with your guide.
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